Funny you should ask !!! ...I have fished Colodado a few times and I fish the Smokies ALOT...... I fished the Flat Top Wilderness area and also The streams around Gunnison......
Without a doubt the fishing is easier and alot more productive in Colorado than in the Smokies. I fished a small stream in Colorado called Cebolla and I must have caught 40-50 browns in the 9-14" range in a half day. The fishing was easier in that we drove right up to the stream and started. The actual streams were not any different than you might find here in the Park. The Taylor River, East River and the Gunnison itself produced larger fish but not as many of them. You are very close to a "fantastic" trout fishing area .....enjoy it