How may flies?
Slider, you can't have too many flies can you? If you can, don't tell my wife!
As far as Smoky patterns, on the LRO website they try to help answer that by breaking flies down into Winter, Spring, Summer and Fall patterns as follows:
Smoky Mountain Winter Flies
Smoky Mountain Spring Flies
Smoky Mountain Summer Flies
Smoky Mountain Fall Flies
All that said, it will be a matter of personal preference on your fly choices. I listen real closely to the veterans of Smoky fly fishing and there is a reason the same type patterns keep being discussed. I think it's because they are proven to work. Just my opinion.