Watch for the bears at 39.
That said, I concur with staying at the front-country campground. It provides access to all the water and is usually quite and peaceful compared to most other front-country sites like Elkmont, Smokemont, etc.
I also agree with Palmer, except I've not caught the size of fish that mtnman talks about. I'd say my average was the typical 7 - 9 inchers common in the Smokies. A few went 10, but these were the exception. I've fished there a half-dozen times and had the same results.