Try a #18 the next time. I swear it will work better, it is more visible and more in line with the size of pupa the fish target. There is little if any nutrional value in a 22, and it is more difficult for a fish to separate it from all the junk floating with the current.
With nymphs on the CLinch the size isn't as critical as the general conformation of the patter. If they are eating midges anything small, thin, and dark will work within reason. Don't fish 14's but you can get away with 18's all day long, and most of the time a 16 will work as well.