Knowledge is the best medicine and the treatments have changed over the years from cutting and sucking to ice packs and so on.
I read one time that more deaths from snakebite incidents involved wrecks on the way to the ER.
We here in Middle TN. have the copperheads,timber rattlers,and pygmy rattlers,(which I've never seen),and the nasty cottonmouths.
The cottonmouth is a snake that is more aggressive than the others in my experience....there's nothing like the adrenaline rush you get when you're chest deep in water and a big one drops into the water beside you.
and yes,they will come after you,I've had it happen more than a couple of times.
I'm glad that they're not in the GSMNP,I would kill myself trying to get away from one on the slippery rocks.