Denver in May

[Hoosier]

Sounds like I am heading to Denver in May for work. I am considering flying out a day or two early and wondered if anyone had any suggestions that woud get me pointed in the right direction. I do not know anything about the area (first time there) but I think I would like to do some small stream fishing similar to what we like about the Smoky's. Any suggestions?

Thanks in advance for any help.